@Prom361: could you please make a list of requirements? Like .NET 4.0, DirectX 9, etc. It would help narrowing down issues with Wine.
Also, is there a way to set the game in windowed mode without launching it? I looked in the .ini files in C:\UDK\RoonSehv\Engine\Config, but couldn’t find one.
So far it seems the main problem is that while installing dotnet40, winetricks deletes mscoree.dll but forget to replace it with the correct version. Come to think of it, the game requiring a 64 bit architecture could also be an issue.